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| Week 1 | Monday, September 10 | Arizona | at | San Francisco | 10:15 PM |
| Week 2 | Sunday, September 16 | Seattle | at | Arizona | 4:05 PM |
| Week 3 | Sunday, September 23 | Arizona | at | Baltimore | 1:00 PM |
| Week 4 | Sunday, September 30 | Pittsburgh | at | Arizona | 4:15 PM |
| Week 5 | Sunday, October 07 | Arizona | at | St. Louis | 1:00 PM |
| Week 6 | Sunday, October 14 | Carolina | at | Arizona | 4:05 PM |
| Week 7 | Sunday, October 21 | Arizona | at | Washington | 1:00 PM |
| Week 9 | Sunday, November 04 | Arizona | at | Tampa Bay | 1:00 PM |
| Week 10 | Sunday, November 11 | Detroit | at | Arizona | 4:15 PM |
| Week 11 | Sunday, November 18 | Arizona | at | Cincinnati | 1:00 PM |
| Week 12 | Sunday, November 25 | San Francisco | at | Arizona | 4:05 PM |
| Week 13 | Sunday, December 02 | Cleveland | at | Arizona | 4:05 PM |
| Week 14 | Sunday, December 09 | Arizona | at | Seattle | 4:05 PM |
| Week 15 | Sunday, December 16 | Arizona | at | New Orleans | 1:00 PM |
| Week 16 | Sunday, December 23 | Atlanta | at | Arizona | 4:05 PM |
| Week 17 | Sunday, December 30 | St. Louis | at | Arizona | 4:15 PM |
Game Time Weather Forecast at Arizona Cardinals  |
